|
Much promise, scant evidence for multicancer early detection tests | |
|
Many cancer researchers agree that multicancer early detection tests, if proven, could help to fill a huge blind spot in cancer screening.
“Despite the limitations, the promise is really great,” said Carmen Guerra, MD, the Ruth C. and Raymond G. Perelman Professor of Medicine.
“I think the Achilles heel of these tests is that they have been offered as multi-cancer early detection tests—emphasizing early—when, in fact, about half of the cases detected through these tests have been early and the other half have unfortunately been late-stage disease.”
|
|
|
|
|
Phase 1 data set the stage for further exploration of cevostamab in multiple myeloma | |
|
Multiple targeted therapies are approved across various settings for patients with relapsed/refractory multiple myeloma, but most patients eventually experience a relapse.
Data from a newly published Phase I clinical trial shows that the investigational bispecific antibody cevostamab could represent an additional approach after other options are exhausted.
“We always love to have more options for our patients,” said lead author Adam Cohen, MD, a professor of Hematology-Oncology and director of Myeloma Immunotherapy.
|
|
|
|
|
New drugs offer ‘a lot of potential’ for multiple myeloma | |
|
Adam Cohen, MD, a professor of Hematology-Oncology and director of Myeloma Immunotherapy, explained how a new class of oral medications known as CELMoDs may fit into the treatment landscape for multiple myeloma.
|
|
|
|
|
Geriatric oncology, clinical trials, and career advice | |
|
Ramy Sedhom, MD, co-Lead for Geriatric Oncology at Penn Medicine, and medical director of Oncology and Palliative Care at Princeton Health, discussed landmark trials in supportive oncology, how to scale geriatric and caregiver-support programs across a health system, work-life balance, avoiding burnout, and more.
|
|
|
|
|
Artificial intelligence in cancer immunotherapy | |
|
Modern AI can sift through genomic, proteomic, and clinical datasets to nominate promising immunotherapy targets or drug concepts. For example, a Penn Medicine team recently built a human-in-the-loop AI pipeline that scanned thousands of single-cell tumor profiles with large language models to rank CAR T targets for melanoma.
|
|
|
|
|
Mid Penn Bank hosts 11th annual celebrity golf tournament to support breast cancer research, awareness
|
|
|
Mid Penn Bank hosted its 11th annual Mid Penn Bank Celebrity Golf Classic in Hershey, PA, in support of the PA Breast Cancer Coalition, the Basser Center for BRCA at Penn Medicine, and the Pink Roses Teal Magnolias Fund at MD Anderson Cancer Center at Cooper Health.
The multi-day event brought together over 60 celebrities, dozens of sponsors, and community partners to raise awareness and funding for breast cancer research, legislative advocacy, high-quality screening, diagnosis, and treatment.
|
|
|
|
|
|
|
|
|
